CoCo headed to TBS!

The late-night guessing game is over, with a startling twist: Conan O'Brien has chosen TBS as his future talk-show home.

Expected to debut in November, the as-yet-untitled show will return O'Brien to the air after an absence that began in January when he abruptly left NBC, his employer of 17 years.

O'Brien's new program will air Mondays through Thursdays at 11 p.m. Eastern, which will shift "Lopez Tonight," starring George Lopez, from 11 p.m. EDT to midnight.

The five-year contract gives O'Brien ownership of the show, according to a person familiar with the deal who spoke on condition of anonymity because the person was not authorized to publicly discuss it.

TBS said that talks with O'Brien accelerated last week after Lopez called O'Brien to ask him to come aboard.

"I can't think of anything better than doing my show with Conan as my lead-in. It's the beginning of a new era in late-night comedy," Lopez said in a statement released by TBS.